This Month in Psychopharmacology

NRX-101 Development Expanded to Include TMS for Depression

Treatment resistance is common in major depressive disorder, and tr...

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Heart Rate, Cholesterol, and Weight Shifts Vary Widely Across Antidepressant Classes

Antidepressants remain among the most prescribed psychotropics worl...

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FDA Approves Lumateperone as Adjunctive Treatment for Major Depressive Disorder

The FDA has approved lumateperone as an adjunctive therapy with an...

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Lurasidone Efficacious for Depression Across Psychiatric Diagnoses

Depressive symptoms are a key driver of morbidity across multiple p...

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Antidepressant Discontinuation Symptoms

Understanding the true incidence and severity of antidepressant dis...

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Esketamine Monotherapy in Adults With Treatment-Resistant Depression

A new phase 4 randomized controlled trial evaluated the efficacy of...

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Lithium Versus Quetiapine Augmentation For Treatment-Resistant Depression

A major randomized controlled trial compared the long-term clinical...

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Esketamine Combinations in TRD: SNRI vs SSRI Outcomes

In a large real-world comparative effectiveness study involving ove...

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Psilocybin and Escitalopram Show Distinct Brain Effects in Depression Treatment

A new randomized controlled trial directly compared the brain effec...

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Trial Results of Solriamfetol in MDD With/Without Excessive Daytime Sleepiness

A new phase 3 proof-of-concept trial offers early evidence that sol...

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Accelerated Theta-Burst Stimulation for Treatment-Resistant Depression

A recent study provides compelling evidence supporting the use of a...

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New Research Links Depression to Increased Risk of Multiple Chronic Diseases

Mood disorders are increasingly viewed as whole-body conditions aff...

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