Ketamine Transiently Alters Brain Network Dynamics Linked to Rumination and Somatosensory Processing
September 22, 2026
Ketamine produces rapid antidepressant effects and has been report...
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DT120 Lysergide ODT Receives FDA Breakthrough Therapy Designation for Major Depressive Disorder
September 15, 2026
Definium Therapeutics announced on September 8, 2026, that the US F...
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Low-Dose Buprenorphine May Enhance Ketamine's Antisuicidal Effects in Major Depression
July 9, 2026
Suicidal ideation in major depressive disorder (MDD) is a major cli...
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Choosing an Adjunctive Antipsychotic for Major Depressive Disorder
May 6, 2026
Most patients with major depressive disorder (MDD) do not achieve f...
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Esketamine for Depressed Adolescents at Imminent Suicide Risk
April 7, 2026
Adolescents with depression have approximately a fivefold increased...
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Exercise Demonstrates Moderate Effects for Depression and Anxiety Across the Lifespan
March 19, 2026
A recent meta-meta-analysis examining the effects of structured exe...
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Rethinking Mood Disorder Treatment with Immunometabolic Insights
March 17, 2026
While there are many stimulant and non-stimulant options targeting ...
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Ketogenic Diet Shows Modest Short-Term Benefit in Treatment-Resistant Depression
March 5, 2026
Studies have suggested that a ketogenic diet –a high-fat, low-carbo...
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Serial Intravenous Ketamine Infusions Not Superior to Usual Inpatient Care for Depression
February 9, 2026
Serial IV ketamine infusions are increasingly used off-label for tr...
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NRX-101 Development Expanded to Include TMS for Depression
January 15, 2026
Treatment resistance is common in major depressive disorder, and tr...
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Heart Rate, Cholesterol, and Weight Shifts Vary Widely Across Antidepressant Classes
December 18, 2025
Antidepressants remain among the most prescribed psychotropics worl...
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FDA Approves Lumateperone as Adjunctive Treatment for Major Depressive Disorder
November 6, 2025
The FDA has approved lumateperone as an adjunctive therapy with an...
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