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Vortioxetine in Patients with Major Depressive and Alcohol Use Disorders
April 17, 2022
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Major depressive disorder (MDD) is often found comorbid with alcohol use disorder (AUD) and patients with MDD+AUD often have a worsened illness and prognosis. Response of MDD+AUD to classic antidepressants, including selective serotonin reuptake inhibitors (SSRIs), norepinephrine serotonin reuptake inhibitors (SNRIs) and tricyclic antidepressants (TCAs) is often unsatisfactory. In this study... |
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Prolonged Grief Disorder Diagnostic Criteria in DSM-5-TR
March 23, 2022
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New diagnostic criteria for prolonged grief disorder (PGD) have been presented in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR). PGD not only places patients at risk for intense distress, but also poor physical health, shortened life expectancy, and suicide... |
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Research Identifies Differences Between Acute LSD and Psilocybin
March 19, 2022
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As interest grows for using lysergic acid diethylamide (LSD) and psilocybin in psychiatric research and therapy, studies comparing the two are necessary. A study with a double-blind, placebo-controlled, crossover design and five experimental test sessions investigated acute responses to... |
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Neural Circuits Of Anxiolytic And Antidepressant Pherine Molecules
March 16, 2022
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Pherines are a novel class of synthetic neuroactive steroids formulated to engage human nasal chemosensory receptors. They are administered intranasally and detected by olfactory afferents wired directly to the limbic amygdala. Due to this mechanism, they have rapid and potent effects on behavior and the autonomic nervous system... |
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