This Month in Psychopharmacology

Browsing articles in "Anxiety/Stress-Related Disorders"

ADHD as a Risk Factor For Being Involved in Intimate Partner Violence
October 12, 2023

In this systematic review and meta-analysis of 14 studies including over 1 million individuals, researchers investigated the relationships between ADHD and violence. The authors found that individuals with ADHD are more likely to be involved in both IPV...

Written Exposure Therapy for PTSD
September 10, 2023

Posttraumatic stress disorder is relatively common among military veterans and typically requires lengthy interventions to treat. These interventions involve 8 to 15 sessions and last between 60 to 90 minutes and utilize between-session assignments. ....

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High-Quality Sleep Promotes Resilience to Depression and Anxiety
July 27, 2023

Chronic stress, and an individual’s resilience in handling it, can greatly impact mental health. One variable that affects an individual’s response to stress is cognitive emotion regulation, which requires a certain amount of executive control. Adaptive cognitive emotion regulation strategies ..

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Psychedelics and PTSD
July 19, 2023

At this moment, of the two drugs, MDMA-assisted psychotherapy has shown the most promise as a treatment for PTSD and recently gained even more traction after successful phase 3 trials. Specifically, a recent study conducted by Dr. Jennifer Mitchell and her colleagues at MAPS found that MDMA-assisted psychotherapy resulted in..

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Psilocybin May Help to Treat PTSD
June 26, 2023

Posttraumatic stress disorder (PTSD) is a chronic mental disorder that occurs after experiencing a traumatic event. Patients with PTSD often have reduced hippocampal neuroplasticity and smaller hippocampal volume compared to healthy individuals. Fear extinction, the process of learning that a previously feared stimulus is no longer threatening, is impaired in PTSD...

Escitalopram Approved for Generalized Anxiety Disorder in Children
May 21, 2023

The U.S. Food and Drug Administration has approved escitalopram for the treatment of generalized anxiety disorder in pediatric patients 7 years of age and older. The expanded pediatric approval was based on data from an 8-week, flexible-dose study that compared escitalopram…

Epigenetic Association With MDMA-Assisted Therapy Treatment Response For Severe PTSD
March 6, 2023

ost-traumatic stress disorder (PTSD) has historically been difficult to effectively treat. However, there is tremendous promise with the renewed study of psychedelic (e.g., MDMA)-assisted therapy. Phase 2 and 3 trials have shown a significant improvement in PTSD symptoms with MDMA-assisted psychotherapy compared to placebo-assisted psychotherapy...

The Future of Psychopharmacology
February 9, 2023

It is an incredible time in terms of the development of new psychopharmacological agents with novel mechanisms of action. In this article, leading experts in the field of psychopharmacology discuss the most promising medications in Phase II and III clinical trials that are being investigated for schizophrenia, bipolar disorder, major depressive disorder, anxiety, substance use disorders, and dementia...

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Aerobic Exercise Augments PTSD Therapy
January 4, 2023

Post-traumatic stress disorder (PTSD) treatment typically involves integrating exposure therapy into a patient's treatment strategy, however, there has been a lack of success in the reduction of PTSD symptoms in response to exposure therapy. In order to enhance the therapeutic effects of exposure therapy, A recent study proposed that aerobic exercise immediately following the therapy session would increase the positive effects of exposure therapy....

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Benzodiazepines Tied to Drug Overdose in Young People With Sleep Disorders
December 15, 2022

In a recent cohort study, the relationship benzodiazepines versus alternative medications prescribed for sleep disorders and increased risk of drug overdose in adolescents was examined. The study included participants diagnosed with a sleeping disorder between the age of 10 to 29 years of age between January...

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