Update to VA/DoD Suicide Assessment and Management Guidelines
September 18, 2019   

Suicide risk among both active and veteran US military members is an increasing concern and is elevated compared to the general population. In fact, approximately 20 US veterans die by suicide every day -most often through...
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Olanzapine Augmentation During Remission From Psychotic Depression: Benefit vs. Risk
September 15, 2019   

A recently published randomized trial found that among patients with psychotic depression in remission, continuing sertraline plus olanzapine reduced the risk of relapse over when compared with sertraline ...
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Metformin Use During Pregnancy May Affect Growth of Offspring
September 12, 2019   

A recent systematic review and meta-analysis compares metformin to insulin for treatment of gestational diabetes mellitus and how it each may alter the growth trajectories from the time of fetal exposure to childhood. Despite...
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National Survey on Drug Use and Health: Trends in Marijuana Use, Prescription Drug Misuse, Major Depressive Episodes, and Other Health Measures
September 8, 2019   

The Substance Abuse and Mental Health Services Administration (SAMSA) recently released their annual national report, based on data from the 2018 National Survey on Drug Use and Health (NSDUH)...
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Degree of Serotonin Reuptake Inhibition and Risk of Ischemic Stroke
September 3, 2019   

Untreated depression has been reported to be associated with cardiovascular disease, thus patients with increased risk for ischemia have been prescribed antidepressants. Previous research also suggests that strong inhibitors may reduce the risk of arterial ischemic activity, however...
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New Medication Approved For Excessive Daytime Sleepiness in Narcolepsy
August 26, 2019   

Narcolepsy is a disorder of hypersomnolence in which the patient experiences intrusion of sleep during periods of wakefulness; it is often accompanied by excessive daytime sleepiness. On August 14, 2019, the FDA approved the ...
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Childhood Maltreatment and Adult Amygdala Function: Timing Matters
August 16, 2019   

Abnormal patterns of hyperactive and hypoactive amygdala responses have been associated with inappropriate social behaviors. Childhood maltreatment is often...
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Vascular Disease is a Major Cause of Mortality Following Inpatient Psychiatric Discharge
August 13, 2019   

In a recent meta-analysis, researchers looked at short- and long-term causes of mortality after inpatient psychiatric discharge. In the short-term period following discharge, mortality rates due to unnatural causes were equivalent to...
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Meta-analysis: Comparative Efficacy and Tolerability of Antipsychotics
August 5, 2019   

A recent network meta-analysis, the largest to date, examined 32 different first-generation and second generation antipsychotics or placebo. Based on 402 studies including 53,463 participants on both placebo-controlled and...
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Moderate Alcohol Consumption and Quality of Life
July 29, 2019   

A recent study looked at two cohorts to evaluate the associations between changes in moderate alcohol consumptions and quality of life from two distinct populations, the United States and Hong Kong. Researchers found that lifetime alcohol abstainers...
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