This Month in Psychopharmacology

Esketamine for Depressed Adolescents at Imminent Suicide Risk

Adolescents with depression have approximately a fivefold increased...

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Exercise Demonstrates Moderate Effects for Depression and Anxiety Across the Lifespan

A recent meta-meta-analysis examining the effects of structured exe...

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Rethinking Mood Disorder Treatment with Immunometabolic Insights

While there are many stimulant and non-stimulant options targeting ...

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Ketogenic Diet Shows Modest Short-Term Benefit in Treatment-Resistant Depression

Studies have suggested that a ketogenic diet –a high-fat, low-carbo...

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Serial Intravenous Ketamine Infusions Not Superior to Usual Inpatient Care for Depression

Serial IV ketamine infusions are increasingly used off-label for tr...

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NRX-101 Development Expanded to Include TMS for Depression

Treatment resistance is common in major depressive disorder, and tr...

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Heart Rate, Cholesterol, and Weight Shifts Vary Widely Across Antidepressant Classes

Antidepressants remain among the most prescribed psychotropics worl...

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FDA Approves Lumateperone as Adjunctive Treatment for Major Depressive Disorder

The FDA has approved lumateperone as an adjunctive therapy with an...

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Lurasidone Efficacious for Depression Across Psychiatric Diagnoses

Depressive symptoms are a key driver of morbidity across multiple p...

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Antidepressant Discontinuation Symptoms

Understanding the true incidence and severity of antidepressant dis...

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Esketamine Monotherapy in Adults With Treatment-Resistant Depression

A new phase 4 randomized controlled trial evaluated the efficacy of...

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Lithium Versus Quetiapine Augmentation For Treatment-Resistant Depression

A major randomized controlled trial compared the long-term clinical...

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