The U.S. Food and Drug Administration (FDA) has approved a labeling update for all antipsychotic medications adding a new warning to the prescribing information. Antipsychotics may cause somnolence, postural hypotension, motor and sensory instability, which may lead to falls and, consequently, fractures or other injuries. For patients with diseases, conditions, or medications that could exacerbate these effects, complete fall risk assessments when initiating antipsychotic treatment and recurrently for patients on long-term antipsychotic therapy.