Browsing articles in "Unipolar Depression"


Disappointing Results for Deep Brain Stimulation in Treatment-Resistant Depression
November 10, 2017   

A recent prospective RCT trial was conducted to test the safety and efficacy of deep brain stimulation (DBS) of the subcallosal cingulate white matter for treatment-resistant depression...
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Increased Risk of Type 2 Diabetes in Pediatric Patients Taking Antidepressants
November 1, 2017   

A newly published study found there an increased risk for youths to develop type 2 diabetes with current use of antidepressants. The antidepressant subclass, duration of antidepressant use, cumulative antidepressant dose, and average daily dose were...
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Perinatal Antidepressant Use and Psychiatric Disorders in Offspring
September 29, 2017   

A recent Danish cohort study examined the association between in utero exposure to antidepressants and risk of psychiatric disorders...
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New Mega-Analysis Supports Efficacy of Antidepressants in Adult Depression
September 12, 2017   

Recently, there has been much debate regarding the efficacy of antidepressants in the treatment of adults with major depressive disorder (MDD) due to the often-high levels of response to placebo in many clinical trials...
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SSRIs, SNRIs Show Small But Significant Benefit for Children and Adolescents With Common Mental Illnesses
September 11, 2017   

There continues to be much debate over the utility and risk-to-benefit ratio of antidepressant use within the pediatric population. In the present meta-analysis, Locher and colleagues investigated the safety and efficacy of selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs)...
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Pediatric Suicide: Age Matters
June 20, 2017   

In the United States, the 4th leading cause of death among children age 5-14 years is suicide. In this study, Peyre and colleagues compared risk factors for suicide attempt in children and adolescents...
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Results from the Predictors of Remission in Depression to Individual and Combined Treatments (PReDICT) Study
May 3, 2017   

Effectively treating major depressive disorder (MDD) is commonly an exercise in trial-and-error and, unfortunately, it takes time (6-12 weeks) in order to deem a particular treatment ineffective before trying a different treatment strategy...
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Depression is the Leading Cause of Disability Worldwide
April 7, 2017   

According to the latest estimates from the World Health Organization (WHO), more than 300 million people are now living with depression...
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Probiotic Found in Yogurt Can Reverse Depression Symptoms in Mice
March 17, 2017   

New research has shown that depressive symptoms and behaviors in mice were reversed when the mice were given food containing the probiotic bacteria lactobacillus...
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Guidelines for the Recognition and Treatment of Depression with Mixed Features
March 10, 2017   

The Diagnostic and Statistical Manual of Mental Disorders 5th Edition (DSM-5) incorporated a "mixed features" specifier that recognizes the idea of mood disorders as lying on a spectrum and acknowledges the coexistence of subthreshold symptoms of (hypo)mania during a major depressive episode (or of subthreshold symptoms of depression co-occurring with a manic episode)...
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