Browsing articles in "Unipolar Depression"


New Mega-Analysis Supports Efficacy of Antidepressants in Adult Depression
September 12, 2017   

Recently, there has been much debate regarding the efficacy of antidepressants in the treatment of adults with major depressive disorder (MDD) due to the often-high levels of response to placebo in many clinical trials...
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SSRIs, SNRIs Show Small But Significant Benefit for Children and Adolescents With Common Mental Illnesses
September 11, 2017   

There continues to be much debate over the utility and risk-to-benefit ratio of antidepressant use within the pediatric population. In the present meta-analysis, Locher and colleagues investigated the safety and efficacy of selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs)...
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Pediatric Suicide: Age Matters
June 20, 2017   

In the United States, the 4th leading cause of death among children age 5-14 years is suicide. In this study, Peyre and colleagues compared risk factors for suicide attempt in children and adolescents...
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Results from the Predictors of Remission in Depression to Individual and Combined Treatments (PReDICT) Study
May 3, 2017   

Effectively treating major depressive disorder (MDD) is commonly an exercise in trial-and-error and, unfortunately, it takes time (6-12 weeks) in order to deem a particular treatment ineffective before trying a different treatment strategy...
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Depression is the Leading Cause of Disability Worldwide
April 7, 2017   

According to the latest estimates from the World Health Organization (WHO), more than 300 million people are now living with depression...
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Probiotic Found in Yogurt Can Reverse Depression Symptoms in Mice
March 17, 2017   

New research has shown that depressive symptoms and behaviors in mice were reversed when the mice were given food containing the probiotic bacteria lactobacillus...
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Guidelines for the Recognition and Treatment of Depression with Mixed Features
March 10, 2017   

The Diagnostic and Statistical Manual of Mental Disorders 5th Edition (DSM-5) incorporated a "mixed features" specifier that recognizes the idea of mood disorders as lying on a spectrum and acknowledges the coexistence of subthreshold symptoms of (hypo)mania during a major depressive episode (or of subthreshold symptoms of depression co-occurring with a manic episode)...
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Consensus Statement on Use of Ketamine for Mood Disorders
March 9, 2017   

Based primarily on small-scale studies and numerous case reports, much excitement has been built around the use of ketamine in the treatment of mood disorder...
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Randomized Controlled Trial Shows Potential Benefit of Dietary Improvement for Major Depression
February 13, 2017   

In a recent study, a 12-week adjunctive dietary intervention program called SMILES was tested for the treatment of moderate to severe depression in patients diagnosed with depression...
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Mobile Apps for Depression: Are They Useful?
January 20, 2017   

There are many mobile apps aimed at patients that are intended as supplemental tools to enhance mental health outcomes, but there is little research as to the effectiveness of such products. To evaluate whether patients use these tools as intended, and whether they impact health outcomes, a group of researchers conducted a randomized controlled trial comparing use patterns and clinical outcomes between 3 self-guided mobile apps for depression...
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