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PSYCHOPHARMACOLOGY
Browsing articles in "Unipolar Depression"

 

Risk of Antidepressant-Induced Weight Gain
June 15, 2018   

A population-based cohort study examined the relationship between antidepressant treatment and weight gain over 10 years...
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Updated Recommendations For Treatment of Tardive Syndrome
April 20, 2018   

The American Academy of Neurology (AAN) has released updated recommendations for treatment of tardive syndromes...
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Evidence for Neuroprogression in Untreated Depression: Microglial Activation
March 23, 2018   

New brain imaging research from the Centre for Addiction and Mental Health (CAMH) shows that the brain alters after years of persistent depression...
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UPDATE: New Guidelines Published for Diagnosis and Treatment of Depression in Adolescents in Primary Care
March 7, 2018   

Depression in children and adolescence is an enormous issue, especially given the potential risk for suicide in this young patient population. Unfortunately, in the primary care setting (which is where many patients are initially or solely seen by clinicians) as many as 2/3 of pediatric patients with depressive symptoms are not diagnosed...
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CYP2C19 Genotype Affects Escitalopram Exposure and Therapeutic Failure
February 2, 2018   

A new study shows that genotyping of CYP2C19 can help predict the therapeutic responsiveness to escitalopram and contribute to personalizing antidepressant therapy for the individual patient...
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First Clinical Trial of Intranasal Esketamine Shows Positive Results for Treatment-Resistant Depression
January 20, 2018   

A recent phase 2 clinical trial was conducted to assess the efficacy and safety of intranasal esketamine adjunctive to oral antidepressant therapy in treatment-resistant depression (TRD)...
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Nature vs. Nurture and the Risk of Depression
January 9, 2018   

A Swedish study finds genetics and environment equally contribute to major depression transmission. For the first time large-scale adoption study, researchers have found that the environment you’re raised in is as important as your genes in determining risk for major depression...
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Disappointing Results for Deep Brain Stimulation in Treatment-Resistant Depression
November 10, 2017   

A recent prospective RCT trial was conducted to test the safety and efficacy of deep brain stimulation (DBS) of the subcallosal cingulate white matter for treatment-resistant depression...
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Increased Risk of Type 2 Diabetes in Pediatric Patients Taking Antidepressants
November 1, 2017   

A newly published study found there an increased risk for youths to develop type 2 diabetes with current use of antidepressants. The antidepressant subclass, duration of antidepressant use, cumulative antidepressant dose, and average daily dose were...
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Perinatal Antidepressant Use and Psychiatric Disorders in Offspring
September 29, 2017   

A recent Danish cohort study examined the association between in utero exposure to antidepressants and risk of psychiatric disorders...
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